Unlearn.AI

Accelerating Clinical Development with AI and Digital Twins

Unlearn.AI is a comprehensive scientific intelligence platform designed to streamline clinical trials through the power of artificial intelligence and digital twin technology. By creating AI-generated forecasts of clinical trial participants' expected control outcomes, Unlearn helps pharmaceutical and biotech companies make faster, more confident decisions throughout the entire clinical development lifecycle.

Integrated Solutions for Trial Planning, Monitoring, and Analysis

The platform consists of three interconnected modules that address key decision points in clinical trials:

• TrialPioneer (Plan): An upstream trial design workspace that brings together critical components including Scout (literature and regulatory precedent search), Hindsight (harmonized clinical trial and real-world datasets), and SimLab (trial design scenario modeling)

• Monitor: Continuous patient and site-level clinical data surveillance that detects anomalies as they emerge, using AI-generated patient trajectories rather than generic population-wide cutoffs

• Analyze: Digital twin technology that strengthens trial analyses by reducing variability and improving treatment effect detection, supporting smaller sample sizes and increased statistical power

Proven Results and Regulatory Validation

Unlearn's methodology is qualified by the European Medicines Agency (EMA) and aligned with current FDA guidance. Real-world implementations have demonstrated approximately 33% control arm size reduction and saved over 4 months in enrollment time. The platform has been successfully applied across multiple therapeutic areas including neuroscience, immunology, and metabolic disease.

Trusted by Leading Biopharma

Unlearn partners with top pharmaceutical companies and biotechs including AbbVie, Trace Neuroscience, QurAlis, remynd, VectorY Therapeutics, and ProJenX. These collaborations span active studies in Alzheimer's disease, ALS, and other critical therapeutic areas, helping sponsors reach clinical milestones faster while reducing trial costs and accelerating time to readout.

The Scientific Intelligence Layer

By integrating evidence, modeling, and reasoning into one connected platform, Unlearn ensures that every trial decision builds on the last, with clear rationale and defensible assumptions across review cycles. This enables trial teams to commit with confidence and move faster for patients waiting for new treatment options.